Folic Acid Supplementation Before and After Conception May Lower Autism Risk

iStock_000010712399SmallWe have known for a long time that folic acid, a man-made form of folate, is an important B vitamin that can help prevent major birth defects, most notably those that affect the spine and brain. Now, preliminary findings in a recent study in JAMA present another potential benefit of this important vitamin, if taken before conception and during pregnancy: an association between folic acid supplementation and reduced risk of autism.

The studied involved over 85,000 mothers and their children, born between 2002 and 2008. In children whose mothers took folic acid from 4 weeks before conception through 8 weeks of pregnancy, 0.10% showed signs of autistic disorder, compared with 0.21% in those unexposed to folic acid supplementation. The study’s authors concluded that these findings cannot establish causality; however, they do support prenatal folic acid supplementation.

Folate can be found in many foods such as leafy vegetables and legumes, but most of us cannot get enough from food alone; hence, the need for supplementation. The CDC recommends that women take 400 micrograms of folic acid every day starting at least 4 weeks before conception and every day during pregnancy; however, even if you are not planning pregnancy there are benefits to taking folic acid because it is a critical component in cell creation and renewal. Folic acid is involved in hair, nail and skin growth and new blood cell development to help prevent anemia.

In many countries, including the U.S., several foods such as bread, pasta and cereal are fortified with folic acid to help prevent birth defects. With a growing number of children being diagnosed with autism spectrum disorder, it is even more important to make sure you are getting enough of this B vitamin. Be sure that your vitamins and food labels list 100% recommended daily value of folic acid or 400 mcgs.

 

Chris Just, MSN, CNM
Executive Director of Prenatal Education

 

 

 

 

About Chris Just MSN CNM

Chris is responsible for overseeing the clinical component of the prenatal education programs at Isis and is actively involved with our hospital partnerships and community outreach. She is a certified nurse-midwife with over 20 years of maternity care experience in educational and clinical roles. Chris is co-creator of Mind Body Birth by Isis and a board member of MA Healthy Mothers and Healthy Babies. She is also a member of the MA Special Legislative Commission on PPD Public Education sub-committee and a member of the MA Perinatal Quality Collaborative Educational/Communication sub-committee. Her focus is on increasing access to relevant, evidenced-based education through on-site and online education, scholarships, community classes and social media. A former Peace Corps Honduras volunteer, Chris is also dedicated to coordinating educational services for underserved populations. Chris received a MSN from Yale University and a BA from Middlebury College. She enjoys time with her husband, Jim, and they are proud parents of a young daughter and son.

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